Transplant Rejection
1. Hyperacute
- rgan turns purple as soon as the vascular supply is connected, resulting in nearly immediate transplant loss.
- Due to preformed antibodies that bind to the endothelium of the transplanted organ and damage vessels.
2. Acute (may be multiple episodes)
- see interstitial infiltration of lymphocytes plus damage to small vessel endothelium.
- T-cell mediated with additional humoral component if not treated within a few days.
3. Chronic rejection—slow,
- clinically silent damage to small vessels which ends up as ischemic organ in 5-10 years.
Sumber : Bpk. Dr. Iskandar Zulkarnain
#posting tugas cyberprenership
ahmad baihaqi
NIM 1112503964
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